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Feline Antinol® Veterinary Technical Bulletin

By Antinol Team

Checking all the boxes

  • Independent third party analysis by Cawthron and Callaghan Innovation.
  • Fatty acid analysis and lengthy stability trials.
  • Heavy metal screen: Inorganic Arsenic, lead, cadmium and mercury all less than .1ppm
  • Pesticide screens less than .02 ppm.
  • Microbial screen negative for pathogens
  • Safety studies demonstrating no adverse effects.

Nutritional Analysis?

Each capsule provides 1.7 kcal and consists of 99.7% lipid (50mg of Antinol® PCSO-524® and 100 mg of olive oil for improved extract bioavailability). DHA and EPA account for 10.4% while total PUFAs consisting of additional omega 3s, unique omegas and omega 6s account for 19.54% of the bioactive lipid profile. Vitamin E is present in small but sufficient quantities to prevent fatty acid oxidation. There are no significant quantities of Vitamin A or trace minerals. There is less than .1% carbohydrate and a trace of protein in the lipid extract. Capsules contain bovine based gelatin.

Adverse Reactions to Food?

Reactions to gelatin are considered extremely uncommon. Trace amounts of protein within the capsules are not expected to elicit an allergic response when managing adverse reactions to food. If you have a very reactive or sensitive patient you can pierce the capsule and express the contents onto the food.

Obese Cats

Obese cats can be a challenge to manage.

Appropriate diet choice and daily caloric intake along with increased activity and management of any concurrent osteoarthritis pain will be the foundation of any feline weight loss plan. A loading dose of 2 capsules provides just 3.4 kcal/day.


Hyperthyroidism patients may also present with altered mobility due to increased muscle catabolism and concurrent age related osteoarthritis. Iodine is a nutrient of concern when managing hyperthyroidism. There is no significant iodine in Antinol®.


Pancreatitis in cats is not considered a fat intolerant condition and low fat diets are not the mainstay of therapy.

Idiopathic Hypercalcemia?

Nutrients of concern with idiopathic hypercalcemia include calcium (Ca) and phosphorus (P), the Ca:P ratio,vitamin D and vitamin A levels. Vitamin D levels are not expected to be significant and specific analysis is difficult due to the unique color of the PCSO-524® extract.

There are no significant amounts of calcium or phosphorus or vitamin A in Antinol®.

Safety trials?

A safety study evaluated 21 healthy cats consuming up to 3 times the loading dose. The serum was lipemic at the highest dose but no significant CBC or blood chemistry changes were noted. (need study hyperlink)

Heart Failure or Kidney Disease?

In both of these conditions, key nutrients of concern include sodium and phosphorus. Sodium is of particular concern in congestive heart failure patients. Dietary phosphorus restriction is a key part of prolonging the lives of patients with chronic renal disease. Antinol® adds no significant sodium (< 8 ppm) or phosphorus (<10 ppm) to the diet and may provide specific anti-inflammatory benefits to patients with cardiac and glomerular disease. 

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